Rob is having an online relationship with Lisa. However, he is suspicious that she may not be everything he imagines and asks her to take a test, presumably one for sexually transmitted diseases. However, the twist is that the test is actually a CAPTCHA test, which is intended to prevent automated computer programs from logging into websites and posting spam messages. Lisa fails this test because she is indeed a computer program and not a human.
Panel number two employs foreshadowing when Rob talks about Lisa mentioning products she likes. When the reader first reads this, they think nothing of it and assume they might not have similar tastes in consumer product preferences. However, when it is revealed that she is a spambot, it becomes clear that she was really interspersing advertising into their conversations.
